XVI FISV Congress

XVI FISV Congress

3R: Research, Resilience, Reprise

Reggia di Portici (Naples), Italy • 14-16 September 2022

Reggia di Portici (Naples), Italy
14-16 September 2022



  • 13:30

    Welcome      [Galoppatoio]


    The EMBO Keynote Lecture
    FISV Lecture Riccardo Cortese     [Galoppatoio]EMBO

    Chair: Giulia Piaggio (Rome)

    Angela Nieto (Alicante, Spain)
    Aberrant activation of developmental programs in adult disease


    Coffee Break      [first courtyard]


    Posters vision 1

    P1 • Environmental, Evolutionary and Developmental Biology (odd-numbered posters)     [Room 1]

    P2 • Genetics, Epigenetics and Chromosome Biology (all posters)     [Room 7]

    P4 • Current trends in Biotechnology (odd-numbered posters)     [Room 2]

    P6 • Health and Disease (odd-numbered posters)     [Galoppatoio]


    Takis presentation     [Galoppatoio]


    Preclinics Italia presentation     [Galoppatoio]


    Parallel Symposia

    1a. From plastics revolution to bioplastics evolution     [Galoppatoio]

    Chairs: Raffaele Porta (Naples) and Paola Chiarugi (Florence)

    Vincenzo Busico (Naples)
    The plastics revolution: a critical review

    Loredano Pollegioni (Varese)
    Plasting-eating enzymes: a protein engineering study

    Loredana Mariniello (Naples)
    Additives and processing aids for bio-based plastics from renewable sources

    Fabrizio Adani (Milan)
    Bioplastic in the circular economy

    1b. Diversity and evolution of genomes     [Room 1]

    Chairs: Omar Rota-Stabelli (Trento), Maria Raffaella Ercolano (Naples), Luca Sineo (Palermo)

    Manuela Sironi (Lecco)
    Evolutionary genomics of human coronaviruses

    Donato Giovannelli (Naples)
    Trace elements, proteins and biogeochemistry: a comparative genomic perspective

    Giorgio Bertorelle (Ferrara)
    Reference genomes and whole-genome resequencing for biodiversity conservation

    Stefania Vai (Florence)
    Surfing on the evolution of the human genome


    AMA Choir in concert     [Galoppatoio]
    La natura in musica


    Welcome cocktail     [first courtyard]

  • 9:00-11:00

    Parallel Symposia

    2a. Microbiome modulation for improving human and plant health     [Galoppatoio]

    Chairs: Franco Faoro (Milan) and Loredana Baccigalupi (Naples)

    Gabriele Berg (Graz, Austria)
    The plant microbiome explored: implications for plant as well as planetary health

    Maria Rescigno (Milan)
    The microbiota and the immune system in gut-liver-brain axis

    Duccio Cavalieri (Florence)
    Microbiome and the gut-brain axis

    Silvia Perotto (Turin)
    Synergistic and complementary interplay between roots and associated microorganisms to boost plant resilience

    2b. The COVID-19 pandemic/tsunami: a scientific revolution from mechanisms to drugs     [Room 1]

    Chairs: Giulia Piaggio (Rome) and Gianni Sava (Trieste)

    Mario Capasso (Naples)
    Human genetic susceptibility to COVID-19: implications in prevention and treatment

    Giuseppe Nocentini (Perugia)
    How the pandemic has changed the research and development paradigms of drugs and vaccines

    Mirko Cortese (Naples)
    Molecular and structuraldeterminants of SARS-CoV-2-induced cellularremodeling

    Marta Giovanetti (Rome)
    Facing the coronavirus crisis: genomic evolution of SARS-CoV-2


    Coffee Break     [first courtyard]


    Tavola rotonda     [Galoppatoio]

    Chairs: Michele Morgante (Udine) and Gennaro Ciliberto (Rome)

    Nuove opportunità per la ricerca Italiana. Responsabili
    Centro Agritech: Matteo Lorito
    Centro RNA: Rosario Rizzuto
    Centro Biodiversità: Danilo Porro


    Lunch Break     [first courtyard]


    Posters vision 2

    P1 • Environmental, Evolutionary and Developmental Biology (even-numbered posters)     [Room 1]

    P3 • Genomics, Proteomics and Systems Biology (all posters)     [Room 8]

    P4 • Current trends in Biotechnology (even-numbered posters)     [Room 2]

    P5 • Food and Nutrition (all posters)     [Room 7]

    P6 • Health and Disease (even-numbered posters)     [Galoppatoio]


    Parallel Symposia

    3a. Plant adaptation and resilience to climate change     [Galoppatoio]

    Chairs: Maria Manuela Rigano (Naples) and Francesco Loreto (Naples)

    JosepPeñuelas (Barcelona, Spain)
    Climate and nutrient imbalances as drivers of a recent global decline in the effects of CO2 and nitrogen fertilization on vegetation growth

    Luisa Maria Sandalio (Granada, Spain)
    Reactive oxygen species in the interface of environmental changes sensing and plant resilience

    Anca Macovei (Pavia)
    DNA Damage Response (DDR) and genome stability at the crossroad between plant development and stress resilience

    Matthew Haworth (Florence)
    Stomatal control of photosynthesis in response to past and potential future climate change

    3b. Updates in neuroscience: a comparative and phylogenetic glance     [Room 1]

    Chairs: Roberto Feuda (Leicester, UK) and Giuditta Gambino (Palermo)

    Emiliano Bruner (Burgos, Spain)
    Fossils and neurosciences: synergies for evolutionary anthropology

    Maria Ina Arnone (Naples)
    The journey of a nerve net towards a brain: a lesson from the sea urchin

    Marina Boido (Turin)
    Neuromuscular junctions: from development to aging and disease

    Marco Rasile (Milan)
    Effects of maternal immune activation on the offspring’s neurovascular unit


    Coffee break     [first courtyard]


    Cornelius Gross (EMBL, Monterontondo)      [Galoppatoio]
    The Future of Molecular Biology – the EMBL Perspective


    Societies' time

    AGI     [Room 1]
    SIB      [Room 2]
    SIBV     [Room 7]
    SIMAG     [Room 8]


    Social dinner at Villa Signorini
    (only for participants who signed up for the dinner)

  • 8:45-9:45

    FEBS National Lecture     [Galoppatoio] FEBS

    Chairs: Paola Chiarugi (Florence) and Martino Bolognesi (Milan)

    Carlo Catapano (Institute of Oncology Research, Università della Svizzera italiana, Bellinzona, Switzerland)
    Mitochondrial plasticity and stemness in human cancers


    Sequentia presentation     [Galoppatoio]


    Coffee Break     [first courtyard]


    6 Parallel Mini Symposia

    • 1. Environmental, Evolutionary and Developmental Biology     [Room 1]

      Chairs: Michela Zottini (SIBV), Alessandro Achilli (AGI), Emiliano Trucchi (SIBE)

      Maria Teresa Vizzari (Ferrara)
      Robust demographic inference from low-coverage whole-genome data through Approximate Bayesian Computation

      Sara Del Duca (Sesto Fiorentino)
      Molecular mechanisms for the evolution of gene structure and organization: the histidine case

      Anna Olivieri (Pavia)
      Barn swallows: mitogenome relationships and phylogeography

      Andrea Silverj (San Michele all'Adige)
      Large-scale genome reconstructions from human gut metagenomes to study phage-host relationships

      Sonia Renzi (Sesto Fiorentino)
      The transition from a traditional to a Western lifestyle and its effect on the interrelation between diet, gut microbiome and health

      Costanza Cannariato (Florence)
      A molecular portrait of ancient Pompeians

      Serena Capitanio (Turin)
      Investigating the role of clathrin-mediated endocytosis in Myc-factors perception in arbuscular mycorrhizas

      Edoardo Tosato (Bologna)
      The likely role of Arabidopsis thaliana cytochromes b561 in intracellular ascorbate redox homeostasis and ROS-mediated signaling

      Andrea Pagano (Pavia)
      Genotoxic damage and nucleolar stress response in primed and overprimed Medicago truncatula seeds

      Serena Farrotti (Rome)
      The air is dry: an integrative quest to safeguard crops from a hotter and drier future

      Riccardo Di Mambro (Pisa)
      Auxin dynamics during developmental programmed cell death events in the Arabidopsis root

      Simone Landi (Naples)
      The circle of reductants to respond to low temperature: the role of the oxidative pentose pathway

    • 2. Genetics, Epigenetics and Chromosome Biology     [Room 7]

      Chairs: Domenico Carputo (SIGA), Gianni Cenci (AGI), Tiziana Bonaldi (SIBBM), Fulvio Chiacchiera (SIBBM)

      Giovanni Messina (Rome)
      Evolutionary conserved relocation of chromatin remodeling complexes to the mitotic apparatus: a new class of moonlighting proteins preventing genetic instability

      Fulvio Chiacchiera (Trento)
      ARID1A preserves tissue homeostasis by preventing genomic instability and chronic inflammation

      Rodolfo Negri (Rome)
      A truncated and catalytically inactive isoform of KDM5B histone demethylase accumulates in breast cancer cells and regulates H3K4 tri-methylation and gene expression

      Stefano Zoroddu (Sassari)
      Recovery of the correct balance of EZH2 and EZH1 proteins as a new strategy for the treatment of rhabdomyosarcoma

      Liliana Tullo (Rome)
      Assessing an unprecedented role for Heterochromatin Protein 1a (HP1a) at

      Romina Burla (Rome)
      The nuclear envelope-associated ESCRT factor CHMP7 is needed for telomere integrity

      Francesca Gorini (Naples)
      8-oxodG accumulation within super-enhancers marks fragile CTCF-mediated chromatin loops

      Tiziana Angrisano (Naples)
      Retinoic Acid promotes a totipotent-like stem cell through Zscan4 epigenetic activation

      Vittoria Brambilla (Milan)
      Molecular control of flowering in rice

      Sebastiano Giallongo (Catania)
      Lactate rewires uveal melanoma metabolic profile promoting cellular quiescence

      Armando Di Palo (Caserta)
      The long non-coding RNA SPACA6-AS1, miR-125a and its mRNA targets establish a novel ceRNA regulatory network in hepatocarcinoma cells

      Cinzia Calvio (Pavia)
      The power of SwrA: from a minor protein to a game changer in B. subtilis biofilms

    • 3. Genomics, Proteomics and Systems Biology     [Room 9]

      Chairs: Maria Benedetta Mattei (SIBV), Alessio Mengoni (SIMGBM), Gianni Cuda (SIBBM)

      Martina Aulitto (Naples)
      Genomic analysis reveals new insights into the biotechnological and industrial potential of Weizmannia coagulans

      Mariarita Brancaccio (Naples)
      Identification of key microRNAs in preeclampsia by bioinformatics analysis

      Sara Bruschini (Rome)
      Leveraging malignant pleural effusions from lung adenocarcinoma patients to investigate the immune landscape of advanced non-small cell lung cancer

      Lisa Cangioli (Sesto Fiorentino)
      Study of the regulatory cascade involved in the megaplasmids conjugation in the model plant symbiotic bacterium Sinorhizobium meliloti by the creation of a GFP-based reporter system

      Michele Costanzo (Naples)
      Proteomic study of the interactions of MMACHC protein

      Guido Domingo (Varese)
      Phosphoproteomic analysis reveals novel mechanisms by which cAMP affects cellular processes and response to heat in tobacco cells

      Nicolaj Jeran (Milan)
      Study of three putative Plastid Peptide Transporters mediating chloroplast-to-nucleus signalling in response to folding stress in Arabidopsis thaliana chloroplasts

      Cristiana Lucia Rita Lipari (Catania)
      Deletion of VDAC1 in human cells affects mitochondrial respiration

      Michele Menotta (Urbino)
      Multi-omics approaches for ataxia telangiectasia therapy development

      Elena Perrin (Sesto Fiorentino)
      A system biology approach to study microbial adaptation to global warming

      Francesca Pirozzi (Naples)
      A specific lipidomic signature defines serum lipid content of patients affected by glycogen storage disease Ia (GSDIa)

      Anna Santin (Naples)
      Integrative molecular analyses and first functional characterization of low-affinity nitrate transporters in diatoms, diNPFs

    • 4. Current trends in Biotechnology     [Room 2]

      Chairs: Rachele Isticato (SIMGBM), Matteo Ballottari (SIBV), Vittoria Brambilla (SIBBM SIGA), Gerardo Puopolo (SIPAV)

      Ivan Baccelli (Sesto Fiorentino)
      New fungicides inspired by natural molecules: plant disease protection by targeted modifications of the Trichoderma peptaibol Trichogin GA IV

      Michele Perazzolli (San Michele all'Adige)
      Taxonomic and functional analysis of the microbiota associated with cold-adapted plants

      Sara Ragucci (Caserta)
      Sodins, ribosome-inactivating proteins from Salsola soda L.

      Michela Cecchin (Verona)
      RNA interference-based techniques to increase sustainability and safety in the fruit and vegetable supply chain

      Tania Vanzolini (Urbino)
      Development of new biological drugs for the treatment of fungal infections

      Nicola Zambrano (Naples)
      Strategies for development of H. simplex-based oncolytic viruses in cancer immunotherapy

      Massimo Zollo (Naples)
      Long-chain polyphosphates impair SARS-CoV-2 infection and replication: prophylactic and therapeutic options against the 6th wave

      Daniela Eletto (Fisciano, SA)
      Potential role of trefoil factor 1 as bioactive peptide in Helicobacter infection

      Miriam Carbonaro (Naples)
      More than just a cellulase: Cel9_Am a new multifunctional GH9 enzyme from Alicyclobacillus mali FL18

      Riccardo D’Incà (Rome)
      Solanum lycopersicum CRISPR/Cas9 mutants for a polyamine oxidase gene exhibit improved drought stress tolerance and water-use efficiency

      Gabriella Fiorentino (Naples)
      A hyperthermoactive-Cas9 editing tool reveals the role of an arsenite methyltransferase in the arsenic resistance system of Thermus thermophilus HB27 and provides a new sensitive arsenic bioreporter

      Valeria Bontà (Pavia)
      Applications of engineered Bacillus subtilis strain for agri-food waste valorization

    • 5. Food and Nutrition     [Room 8]

      Chairs: Katia Petroni (AGI), Francesca Marcon (SIMAG), Stefania Iametti, Francesco Bonomi (SIB)

      Stefany Castaldi (Naples)
      Halotolerant PGP Bacillus amyloliquefaciens enhance the salinity stress tolerance of Lotus japonicus cv gifu

      Maurizio Chiurazzi (Naples)
      LjNRT2.3 plays a hierarchical role on the control of root nitrate uptake in L. japonicus

      Nadia Lombardi (Portici, NA)
      Biological treatments of grapevines improve the phenolic composition and sensory properties of Aglianico wine

      Roberta Marra (Portici, NA)
      Sustainable approaches to improve productive and qualitative traits of industrial tomato plants using biostimulants and mulch biofilms

      Francesca Messina (Pavia)
      Sustainable seed priming treatments to improve germination in lettuce

      Angelo Santino (Lecce)
      Biofortification strategies for the improvement of the nutritional value of tomato

      Antonio Caporale (Portici, NA)
      Fostering food safety and quality in Neapolitan contexts of sustainable urban agriculture

      Paola Antonia Corsetto (Milan)
      Selective impact of polyunsaturated fatty acids on lipid composition and metabolism in breast cancer cells

      Mattia Di Nunzio (Milan)
      Modulation of proteolytic activity by dietary polyphenols is dependent on both substrate and enzymes

      Katia Petroni (Milan)
      Anthocyanins confer cardioprotection against Doxorubicin by modulating the AMPK-SIRT1-p53 pathway

      Giuditta Heinzl (Milan)
      Investigating the mechanisms of action of conglutin-γ in regulating D-glucose uptake: the role of intestinal barrier

      Manuela Leri (Florence)
      Olive polyphenols act as biomimetic molecules in hormone replacement therapy for Alzheimer's disease prevention in menopausal women

      Giulia Magni (Milan)
      Purple corn anthocyanins as a nutraceutical approach to control the progression of multiple sclerosis and associated trigeminal pain: role of the gut-brain axis

      Laura Mosca (Naples)
      "Greco" grape canes as a valuable source of bioactive compounds with antioxidant properties and anticancer activity on head and neck squamous cell carcinoma

    • 6. Health and Disease     [Galoppatoio]

      Chairs: Marco Oggioni (SIMGBM), Paola Minghetti (ADRITELF), Giuseppe De Rosa (ADRITELF), Sheridan Lois Woo (SIPAV)

      Andrea Bosso (Naples)
      GVF27, a new human host defence peptide, shows anti-inflammatory and anti-biofilm activity against the Burkholderia cepacia complex (Bcc)

      Lorenzo Ceccarelli (Pisa)
      Human microglia derived Extracellular Vesicles: effects of inflammatory stimuli on production, content, and biological function

      Costanza Cicchi (Florence)
      Characterization of the enzymatic activity of Lscβ and Lscγ, two levansucrases from Pseudomonas syringae pv. actinidiae

      Luigi Fattore (Rome)
      Systemic delivery of miRNA-loaded nanoparticles blunts resistance to therapy in BRAF-mutant melanoma

      Barbara Giordani (Bologna)
      Nanocarriers for the delivery of Lactobacillus crispatus BC1 biosurfactant: alternative strategies to fight Candida biofilms

      Sarah Giulietti (Viterbo)
      Elucidation of the Arabidopsis NPK1-related protein kinases (ANPs) role in cell wall biosynthesis and signalling

      Vittoria Nicolis di Robilant (Rome)
      Inactivation of the nijmegen breakage syndrome protein (NBS1) abrogates SHH-driven cerebellar development/tumorigenesis through the primary cilium

      Marco Rinaldo Oggioni (Bologna)
      Ex vivo perfusion of the human spleen to study infection

      Lara Russo (Pisa)
      Biomimetic scaffolds for tendon/ligament regeneration

      Chiara Siniscalchi (Caserta)
      Human microRNAs binding to SARS-CoV-2 sequences: computational analysis and experimental validation

      Mariavittoria Verrillo (Portici, NA)
      Antiflammatory activity and potential dermatological applications of characterized humic acids from a lignite and a green compost

      Guendalina Zuccari (Genoa)
      Fenretinide-loaded mesenchymal stem cells-derived extracellular vesicles as novel drug carriers against human neuroblastoma


    Lunch Break     [first courtyard]


    Parallel Symposia

    4a. Insights into insect biology to control pathogen vectors and agricultural pests      [Galoppatoio]

    Chairs: Guido Favia (Camerino) and Laura Rinaldi (Naples)

    Guido Favia (Camerino, Italy)
    Microbial symbiosis in insect vectors and insect pests

    Paolo Gabrieli (Milan)
    Digging into the biology of mosquito reproduction to design novel control tools

    Francesco Pennacchio (Naples)
    Insect multitrophic interactions for bioinspired plant protection

    4b.  Spatial profile of gene expression      [Room 1]

    Chair: Lucia Altucci (Naples) and Massimiliano Corsi Romanelli (Milan)

    Raffaele Calogero (Turin)
    Single cell omics integration with spatial transcriptomics

    Tiziana Bonaldi (Milan)
    Unravelling non-genetic inter- and intratumor (epigenetic) heterogeneity by spatial tissue proteomics

    Francesca Ciccarelli (London, UK)
    Unravelling the dynamic interplay between genetics and immunity in driving cancer evolution


    Conclusion and Prizes     [Galoppatoio]

  • Posters will be discussed in presence in the specific parallel sessions, at the time and in the room that are shown in the programme (check the specific day). For Poster Session 1 (Wednesday, 14 September from 15:30 to 17:00), odd-numbered posters will be presented for topics P1, P4 and P6, as well as all posters for topic P2. For Poster Session 2 (Thursday, 15 September from 13:30 to 15:00), even-numbered posters will be presented for topics P1, P4 and P6, as well as all poster for topics P3 and P5.

    • P1 • Environmental, Evolutionary and Developmental Biology

      P1.1 Vincenzo Agostini (Pavia)
      The worldwide spread of Aedes albopictus: new insights from mitogenomes

      P1.2 Francesca Alderotti (Sesto Fiorentino)
      To save water on not to save, that is the question: tree-ring stable isotopes explain the dieback of Quercus ilex in southern Tuscany (Italy)

      P1.3 Deborah Bastoni (Rome)
      Linking plate tectonic settings and microbial functions on a global scale

      P1.4 Agnese Bellabarba (Sesto Fiorentino)
      Exploration of salt tolerance of Sinorhizobium meliloti strains during the first steps of the symbiosis

      P1.5 Manuel Benedetti (L'Aquila)
      Radical cation scavenging activity of berberine bridge enzyme-like oligosaccharide oxidases acting on short cell wall fragments

      P1.6 Alessandro Bevilacqua (Onna, Japan)
      Exploiting bovine serum albumin liquid­-liquid phase separated protocells to unravel enzyme activity tuning dependent on the protocell’s size and composition

      P1.7 Rajiv Boscolo Agostini (Ferrara)
      Reconstructing the global invasion routes of Halyomorpha halys through Approximate Bayesian Computation

      P1.8 Giulia Caioni (L'Aquila)
      Long-term neurotoxicity induced by early-life exposure to propylparaben in zebrafish model

      P1.9 Ilaria Camponeschi (Rome)
      Smuorz e llaits: response of the yeast Kluyveromyces lactis to light

      P1.10 Giorgia Capasso (Naples)
      Characterization of a glucose-6-phosphate dehydrogenase from Chlamydomonas reinhardtii

      P1.11 Benedetta Caraba (Rome)
      Calorie restriction suppresses premature aging in pro-apoptotic LSM4 yeast mutants

      P1.12 Federica Carducci (Ancona)
      Omics approaches as useful tool to provide an exhaustive view of marine species: the case of Chamelea gallina

      P1.13 Federica Casagrande (Rome)
      Characterization of light-dependent regulation of flower opening in model plant Arabidopsis thaliana

      P1.14 Stefano Cazzaniga (Verona)
      Turning a green alga red: astaxanthin biosynthetic pathway in Chlamydomonas reinhardtii improves resistance to light stress and biomass productivity at high irradiances

      P1.15 Costanza Ceccanti (Pisa)
      Responses of photosynthesis and antioxidant system to salinity stress in Beta vulgaris L. under different levels of nitrogen supplementation

      P1.16 Ana Chero Osorio (Pavia)
      Mitochondrial DNA haplogroup X2a: an enigmatic presence among North American Indigenous people

      P1.17 Pasquale Chiaiese (Portici, NA)
      Exposure to transition metals and metalloid to eggplant (Solanum melongena L.) affect ionome and specific metal transporters gene expression

      P1.18 Giulia Colombo (Pavia)
      New insights on past human movements by combining modern and ancient Y-chromosome data in a single phylogeny: the test case of haplogroups C and Q

      P1.19 Ilaria Colzi (Florence)
      Do tomato plants like microplastics? Study of the impact on crop yield and physiology

      P1.20 Lorenzo Cotrozzi (Pisa)
      Hyperspectral assessment of physiological and morphological leaf traits related with drought in three varieties of Aucuba japonica with different leaf variegation

      P1.21 Rossana Cuciniello (Naples)
      Oxidative stress defense impairment affects neuronal differentiation

      P1.22 Rosanna Culurciello (Naples)
      Protective effects of recombinant human angiogenin in HaCaT cells: new insights on skin stress response mediated by RNases

      P1.23 Federica De Lise (Naples)
      Transcription regulation and translational recoding of the alpha-L-fucosidase from Saccharolobus solfataricus in vivo

      P1.24 Maria Concetta de Pinto (Bari)
      GUN1 involvement in the redox changes occurring during biogenic retrograde signaling

      P1.25 Raffaele Dello Ioio (Rome)
      microRNA165 and 166 control plastic development of the Arabidopsis root meristem in response to salt stress

      P1.26 Giovanni Di Gregorio Barletta (Naples)
      CotG controls spore surface formation in response to the temperature of growth in Bacillus subtilis

      P1.27 Conrado Jr Dueñas (Pavia)
      Variation in germination behavior of Italian rice varieties in response to drought and poly-γ-glutamic acid treatments

      P1.28 Antonia Esposito (Sesto Fiorentino)
      Temporal evolution of bacterial communities associated to Phragmites australis exploited in phytodepuration of wastewater

      P1.29 Sergio Esposito (Naples)
      Magnesium di-cations as regulators of plastidic glucose-6P dehydrogenase activity in plants

      P1.30 Anna Fiorillo (Rome)
      Role of Salt Tolerance-Related Protein (STRP) in salt stress responses in Arabidopsis thaliana

      P1.31 Elide Formentin (Padua)
      ROS, cytokinin and high salinity affect primary root development in rice

      P1.32 Giobbe Forni (Bologna)
      Genome evolution in Enterobacteriaceae endosymbionts

      P1.33 Silvana Francesca (Portici, NA)
      Flowering time and leaf morphology traits are key for heat tolerance in one tomato genotype

      P1.34 Ilaria Fraudentali (Rome)
      Role of CuAOβ and RBOHD-derived hydrogen peroxide in wound-induced local and systemic signal propagation leading to stomatal closure in Arabidopsis thaliana

      P1.35 Isidora Gjata (Bari)
      Phytotoxicity of rare earth elements cerium and neodymium in onions and lentils

      P1.36 Adriano Griffo (Pavia)
      Determination of reactive oxygen species (ROS) during seed priming and germination

      P1.37 Libero Gurrieri (Bologna)
      Inhibitory loss of glutathionylation as an alternative regulatory mechanism for Arabidopsis β-amylase 1

      P1.38 Sondos Hejazi (Naples)
      Bio-inspired materials manufactured with poly-γ-glutamic acid and chitosan

      P1.39 Maurizio Iovane (Naples)
      Heat treatment on microsporogenesis affects pollen functionality and timing of pollen ontogenesis

      P1.40 Nataliia Kozak (Pavia)
      Disentangling the genetic history of modern Ukrainians through mitogenomes

      P1.41 Cecilia Lasorella (Bari)
      Chloroplast-localized GUN1 contributes to the acquisition of basal thermotolerance in Arabidopsis

      P1.42 Riccardo Lorrai (Rome)
      Plant cell wall perturbations trigger hormonal changes impairing apical hook development

      P1.43 Francesca Lucibelli (Naples)
      The Phalaenopsis PeDL2 gene is a possible new regulator of labellum development

      P1.44 Francesco Magnanimi (Rome)
      Mechanisms and molecular basis of the effect of natural oils on the development and resilience of plants aimed at the eco- sustainable production of vegetable species

      P1.45 Pina Marotta (Naples)
      Insights into the molecular mechanisms of diatoms life cycle

      P1.46 Carmine Merola (Teramo)
      Is methylparaben an endocrine disrupting-chemical inducing generic toxicity in zebrafish model?

      P1.47 Michela Molinari (Rome)
      A correlation between sulfur and glutathione metabolism in Oryza Sativa under salt stress

      P1.48 Francesco Montemagno (Naples)
      Shark microbiome in the Mediterranean sea: microbiome analysis demonstrates unique microbial communities

      P1.49 Maria Monti (Naples)
      Identification and functional characterization of Toxoneuron nigriceps ovarian proteins involved in the early suppression of host immune response

      P1.50 Elisabetta Moroni (Pavia)
      Analysis of ancient human genomes from a medieval site in Northern Italy

      P1.51 Yuri Luca Negroni (Padua)
      Genetically encoded biosensors in grapevine for studying abiotic stresses

      P1.52 Stefano Nenciarini (Sesto Fiorentino)
      Yeast Extracellular vesicles as means of immunomodulation

      P1.53 Anna Maria Pappalardo (Catania)
      Evidence for selection on mitochondrial DNA in the Mediterranean killifish Aphanius fasciatus Valenciennes, 1821

      P1.54 Chiara Pedalino (Rome)
      Plant as a whole: rapid long-distance signaling mediated by Ca2+-ATPases and glutamate receptor-like channels triggers wound-induced stomatal closure

      P1.55 Elisa Pellegrini (Pisa)
      Early biochemical responses of resistant and susceptible clones of cypress infected with Seiridium cardinale

      P1.56 Matteo Daghio (Florence)
      Poly (lactic acid) biodegradation study in simulated composting bioreactors

      P1.57 Federica Pennisi (Verona)
      Investigation of the role of B-box MicroProteins in the tomato reproductive development

      P1.58 Silvia Perretti (Ferrara)
      Understanding the process of skin lightening in Europeans: selection and migration

      P1.59 Alex Pessina (Milan)
      A novel strategy for ammonia production using yeast

      P1.60 Matteo Pivato (Verona)
      Dissecting the role of intracellular Ca2+ signalling in the responses to the environment in the green microalga Chlamydomonas reinhardtii

      P1.61 Miriam Porretti (Messina)
      Plasticisers content in women’s blood at different ages

      P1.62 Adele Preziosi (Rome)
      2-hydroxyisobutyrate (2-HIBA), an unspecified mammalian metabolite, modulates ageing and fat deposition depending on the high glucose diet in C. elegans animal model

      P1.63 Maria Manuela Rigano (Portici, NA)
      Modulation of AsA biosynthesis and pectin-related gene expression by genetic introgression to enhance resistance to Botrytis cinerea in Solanum lycopersicum

      P1.64 Teresa Rinaldi (Rome)
      Carbonatogenic bacteria on the ‘Motya Charioteer’ sculpture

      P1.65 Antonio Massimiliano Romanelli (Fisciano,SA)
      Cytotoxicity of the emergent environmental pollutant 4-octylphenol in human cell lines

      P1.66 Simone Samperna (Rome)
      Cyclopaldic acid induces PCD and autophagy in Arabidopsis thaliana

      P1.67 Irene Sbrocca (Rome)
      Phenotypical and bio-chemical characterization of durum wheat (Triticum durum) genotypes under salt stress

      P1.68 Valentina Scafati (L'Aquila)
      Characterization of two 1,3-β-glucan acting enzymes from Penicillium sumatraense reveals new insights into 1,3-β-glucan metabolism of fungal saprotrophs

      P1.69 Anna Scortica (L'Aquila)
      Berberine bridge enzyme-like oligosaccharide oxidases act as enzymatic transducers between microbial glycoside hydrolases and plant peroxidases

      P1.70 Matteo Selci (Naples)
      Geobiological processes controlling methane cycling at the Central American convergent margin

      P1.71 Giulia Semenzato (Sesto Fiorentino)
      The phytobiome of the medicinal plant Origanum vulgare: exploring the link between essential oil composition and its associated endophytic communities

      P1.72 Mario Soccio (Foggia)
      Genome-wide analysis and expression profiling of glyoxalase I genes in durum wheat
      (Triticum durum Desf.) under hyperosmotic stress

      P1.73 Francesca Sparla (Bologna)
      The role of sucrose phosphate synthase A2 in directing carbon skeletons along different pathways

      P1.74 Anna Valenti (Naples)
      A proteomic approach to uncover Deformed Wing Virus-honey bee interactions

      P1.75 Margherita Vanni (Florence)
      Genomic analyses of human skeletal remains from the prehistoric site of Corna Nibbia (Bione, Brescia)

      P1.76 Clarissa Zanotti (Rome)
      Analysis of the role and functionality of plant-derived exosome-like nanovesicles (PELNVs): a new research strategy and therapeutic application

      P1.77 Valentina Zaro (Florence)
      A genetic picture of Bologna (Italy) during the Etruscan period

      P1.78 Edgardo Filippone (Portici, NA)
      Ionome-transcriptome data integration from a subset of Solanum pennellii introgression lines reveals traits for tomato fruit mineral content

    • P2 • Genetics, Epigenetics and Chromosome Biology

      P2.1 Roberta Amato (Rome)
      Telomeric replicative stress promotes ALT mechanism in ATRX and p53 depleted cells

      P2.2 Susanna Ambrosio (Naples)
      Dissecting the relationship between DNA repair and autophagy to improve the efficacy of anticancer treatment

      P2.3 Federica Barbato (Rome)
      DNA Damage induced by Ionizing radiation activates the innate immune response: study and characterization of the cGAS-STING pathway

      P2.4 Ludovica Bonanni (Rome)
      The role of BLM and FANCJ DNA-helicases in the response to G-quadruplex-stabilizing ligand RHPS4

      P2.5 Fabio Caradonna (Palermo)
      Clonal evolution in genomically unstable rat astrocyte cell lines: cytogenetic, epigenetic and proteomic study

      P2.6 Pietro Salvatore Carollo (Palermo)
      Inhibition of FTSJ1, a tryptophan tRNA-specific 2’-O-methyltransferase as possible mechanism to readthrough premature termination codons (UGAs) of the CFTR mRNA

      P2.7 Marco Coluccia (Rome)
      Understanding the functional homology of CamA and VirK proteins in Shigella flexneri

      P2.8 Fabio Coppedè (Pisa)
      Gene-environment interactions in autism spectrum disorders (ASD): artificial intelligence reveals sex-specific connections among maternal risk factors and the methylation levels of autism genes as well as the main contributors of symptoms severity in ASD children

      P2.9 Ylenia Cortolezzis (Udine)
      Transcription regulation of Kirsten Ras (KRAS) gene: role of guanine-rich motifs in promoter and 5' UTR

      P2.10 Flora Cozzolino (Naples)
      Lysines Acetylome and Methylome Profiling of H3 and H4 Histones in Trichostatin A–Treated Stem Cells

      P2.11 Elena De Marino (Naples)
      Arf at the crossroad between cancer and differentiation

      P2.12 Antonella Delicato (Naples)
      Involvement of Y-box binding protein 1 (YB-1) in DNA damage and repair mechanisms systems

      P2.13 Maddalena Di Nardo (Pisa)
      SMC1A downregulation as therapeutic target for colon cancer

      P2.14 Camilla Fagorzi (Sesto Fiorentino)
      Unravelling the bacterial epigenome: the role of DNA methylation in gene transfer and gene expression regulation

      P2.15 Margherita Ferretti (Civitavecchia)
      Searching for NF-Y-dependent signalling pathways in the progression from colorectal primary tumor to liver metastases

      P2.16 Alessandro Giampietro (Rome)
      Depletion of the genome integrity-associated factor Ft1 induces DNA damage and cardiac dysfunction in mice

      P2.17 Teresa Giannattasio (Rome)
      The RNA-binding protein FUS/TLS interacts with SPO11 and provides a link with PRDM9-dependent recombination hotspots

      P2.18 Valentino Maria Guastaferro (Portici, NA)
      Root adhesion and cell-to cell fusion are HAM-7-dependent in Fusarium oxysporum

      P2.19 Jessica Marinaccio (Rome)
      TERT role in response to oxidative stress: a putative player into mitochondria

      P2.20 Concetta Montanino (Caserta)
      Genetics and Epigenetics in Palmoplantar keratoderma: a case report

      P2.21 Paola Pagano (Pavia)
      Phenotypic characterization of Arabidopsis thaliana tdp1α and tdp1β mutants subjected to genotoxic stress

      P2.22 Miriam Pagin (Milan)
      Brain gene regulation in 3D: long-range promoter-enhancer functional interaction networks in mouse brain-derived neural stem cells, and their relevance for neurodevelopmental disease

      P2.23 Maria Michela Pallotta (Pisa)
      Cohesin mutations and Wnt agonism: a new therapeutical approach for cancer

      P2.24 Giuseppe Saccone (Naples)
      A single principle for male sex determination in major agricultural pests (Tephritidae): Maleness-on-the-Y (MoY), its evolutionary conservation and its usage for future genetic control

      P2.25 Maria Virginia Santopietro (Rome)
      Beyond chromatin remodeling: evolutionary conserved roles of Drosophila melanogaster Tip60 complex in cell division

      P2.26 Valentina Sassano (Padua)
      Deregulation of dNTP pools in cells derived from patients affected by Friedreich Ataxia

      P2.27 Andrea Stoccoro (Pisa)
      Artificial neural networks revealed several associations between the exposure to various prenatal environmental stressors and DNA methylation levels evaluated in placenta and in mothers and neonates buccal cells

      P2.28 Luca Tadini (Milan)
      Perturbation of protein homeostasis brings plastids at the crossroad between repairment and dismantling

      P2.29 Rita Trirocco (Rome)
      Fatty acids abolish Shigella virulence inhibiting its master regulator VirF

    • P3 • Genomics, Proteomics and Systems Biology

      P3.1 Andrea Becchimanzi (Portici, NA)
      Analysis of the salivary gland transcriptome of the honey bee mite Varroa destructor

      P3.2 Martina Buonanno (Naples)
      Insights into the Winged Helix Domain of P150, a subunit of the Chromatin Assembly Factor-1

      P3.3 Luisa Canè (Naples)
      Characterization of human TSLP isoforms

      P3.4 Ludovica Celli (Pavia)
      Dissecting the involvement of GC-AG introns in alternative splicing regulation

      P3.5 Himanshi Choudhary (Udine)
      Long-term NRF2 depletion in KRAS-mutated pancreatic cancer cells leads to the activation of metabolic short-circuits sustaining cancer cells fitness and overcoming KRAS addiction

      P3.6 Nunzio D'Agostino (Portici, NA)
      Towards the analysis of the transcriptome dynamics to understand the molecular basis of the complex interaction process between the parasitic weed Phelipanche ramosa and tomato

      P3.7 Claudia De Vitis (Rome)
      Multiomic analysis reveals ALDOC and ENO2 as master regulators of cancer stem cells metabolism

      P3.8 Sara Donzelli (Rome)
      PI3KCA-mutant breast cancer metastatic patient-derived organoids envisage Alpelisib treatment for multiple secondary lesions

      P3.9 Francesca Guarino (Catania)
      Regulation of VDAC1 gene expression in HeLa cells mediated by HIF-1α

      P3.10 Alessia Medugno (Naples)
      Involvement of miRNA 137 in hereditary gastrointestinal cancer predispostion trought MSH2 gene regulation

      P3.11 Angela Messina (Catania)
      An emerging role as a biomarker for VDAC1P8 pseudogene in acute myeloid leukemia

      P3.12 Veronica Russo (Caserta)
      MucR is a new prokaryotic histone-like protein

      P3.13 Giovanni Scala (Naples)
      MultiOmics Network Embedding for SubType Analysis

      P3.14 Shraddha Shridhar Gaonkar (Pavia)
      Profiling of LEA proteins in Medicago truncatula dry seed proteome

      P3.15 Federico Vita (Bari)
      Molecular responses to phosphate fertilization in durum wheat plants under different fertilization regimes

      P3.16 Rosita Russo (Caserta)
      Unravelling the CD3+CD56+ T cell proteome by Tandem Mass Tag-Based High-Resolution LC-MS/MS

      P3.17 Mariangela Valletta (Caserta)
      Profiling of lactic acid bacteria in milk kefir by high-resolution tandem mass spectrometry

    • P4 • Current Trends in Biotechnology

      P4.1 Alberto Alfano (Naples)
      Biotech processes towards waste valorization in nutraceutical and cosmeceutical applications

      P4.2 Carmen Bianco (Naples)
      Broad-spectrum activity of endophytes isolated from African rice

      P4.3 Simona Carfagna (Naples)
      Microalgae cross‑fertilization: short‑term effects of Galdieria phlegrea extract on growth, photosynthesis and enzyme activity of Chlorella sorokiniana cells

      P4.4 Martina Cascone (Naples)
      Hydrogenotrophic metabolisms in the subsurface: ecological and biotechnological applications

      P4.5 Corentin Clavé (Portici, NA)
      Plant-mediated effects of the entomopathogenic fungus Beauveria bassiana on Spodoptera littoralis

      P4.6 Sara Colanero (Milan)
      Engineering water use in tomatoes by generating novel allelic variation for ABA signaling genes via Crispr-Cas9. 

      P4.7 Iolanda Corrado (Naples)
      Exploitation of inulin rich biomass for bioplastics production

      P4.8 Salvatore Cubisino (Catania)
      Determination of electrophysiological properties of envelope (E) protein from SARS-CoV-2

      P4.9 Sabrina Cuomo (Naples)
      Holocellulose from Poseidonia oceanica egagropili sea balls: a waste source valorized as enhancer of cellulase biotechnological production by Streptomyces roseochromogenes

      P4.10 Gennaro D'Ambrosio (Portici, NA)
      Phycoremediation of persistent pollutants: Polycyclic Aromatic Hydrocarbons (PHAs) and microplastic debris (MPs)

      P4.11 Sergio D'Ambrosio (Naples)
      Agri-food waste biomasses for the production of Lactic Acid from Lactobacillus rhamnosus IMC501

      P4.12 Caterina D'Angelo (Naples)
      Characterization of a new anti-adhesive molecule from Psychrobacter sp. TAE2020

      P4.13 Giovanna De Leva (Portici, NA)
      Impact of Deformed Wing Virus infection on honey bee gut microbiota

      P4.14 Maria Giovanna De Luca (Portici, NA)
      I funghi benefici del genere Trichoderma sono efficaci agenti di controllo delle larve di falena notturna

      P4.15 Angelo De Paolis (Lecce)
      Biotechnological production of natural agrochemicals by cell cultures of Dittrichia viscosa

      P4.17 Benedetta Di Chiara Stanca (Lecce)
      Chemical, structural and biological characterization of CGF and analysis of its osteogenic potential

      P4.18 Carmen Ercolano (Naples)
      Functional metagenomics approach for the identification of new (hyper)thermophilic carbohydrate-active enzymes of biotechnological interest

      P4.19 Michela Famiglietti (Naples)
      Mechanical, thermal, and barrier properties of amylose-based bioplastics

      P4.20 Arianna Filippelli (Siena)
      Profiling of potential pharmacological activity of sweet chestnut wood distillate as antioxidant and anti-inflammatory agent

      P4.21 Rosa Gaglione (Naples)
      Novel bioactive peptides identified in a protein from human plasma to counteract bacterial infections

      P4.22 Laura Giannotti (Lecce)
      Osteogenic differentiation of CGF cells can be induced by silicon scaffold

      P4.23 Laura Gioia (Portici, NA)
      Reduction of copper-based fungicides use for controlling phytopathogens by Trichoderma application

      P4.24 Moira Giovannoni (L'Aquila)
      Valorization of lignocellulosic wastes for the production of fungal enzymes of industrial relevance

      P4.25 Rachele Ingrisano (Bologna)
      Microalgae: from photosynthetic scavengers to green biofactories

      P4.26 Carmen Laezza (Portici, NA)
      The use of plant cell culture as an alternative method for the production of dihydrochalcones and flavonoid

      P4.27 Giulia Magoga (Milan)
      COins: a reference database of COI sequences for insect species molecular identification

      P4.28 Emanuela Maresca (Naples)
      Alicyclobacillus mali FL18, a promising microorganism for degradation of agri-food wastes: from synthetic substrates to a novel consortium with Weizmannia coagulans MA – 13 on agri – food wastes

      P4.29 Federico Martinelli (Sesto Fiorentino)
      Development of a protocol for CRISPR/Cas9-edited for legumes highly recalcitrant to in vitro regeneration

      P4.30 Rosanna Mattossovich (Naples)
      New DNA-Nanoswitches for Monitoring the Activity of DNA Repair Enzymes

      P4.31 Seyedeh Fatemeh Mirpoor (Naples)
      Manufacture of polyhydroxyalkanoate coated pectin-based bioplastics

      P4.32 Eleonora Montuori (Messina)
      Microalgal compounds with immunomodulatory activities

      P4.33 Ohiemi Benjamin Ocheja (Bari)
      Development of yeast-based biosensor for precision agriculture

      P4.34 Francesca Paragliola (Naples)
      Characterization and engineering of thermophilic α-glucosidase MalA from the hyperthermophilic crenarchaeon Saccharolobus solfataricus

      P4.35 Federico Perozeni (Verona)
      Microalgae for the future: use of Chlamydomonas reinhardtii to produce high value products for a growing population

      P4.36 Simone Pitton (Milan)
      Effective and eco-friendly delivery of a Bacillus thuringiensis-based insecticide in Aedes albopictus larvae

      P4.37 Luigia Principio (Portici, NA)
      Use of CRISPR/Cas9 to study ascorbic acid metabolism in a S. pennellii introgression subline

      P4.38 Yuri Prozzillo (Rome)
      Adaptation of dTAG system in Drosophila melanogaster

      P4.39 Elia Russo (Portici, NA)
      Host-parasitoid developmental interactions are modulated by venom components of Aphidius ervi (Hymenoptera, Braconidae)

      P4.40 Flora Salzano (Naples)
      Eco-friendly extraction of antioxidants from agri-food residues

      P4.41 Emily Schifano (Rome)
      Development of functionalized masks: improvement of personal protective equipment using nanomaterials

      P4.42 Angelica Severino (Naples)
      Pseudoalteromonas haloplanktis TAC125 as host for the recombinant production of the hCDKL5-1 catalytic domain

      P4.43 Alessia Staropoli (Portici, NA)
      Metabolomics for the selection of beneficial microorganisms and/or their metabolites for new bioformulates

      P4.44 Maria Carmen Valoroso (Portici, NA)
      Characterization of immune genes and responses to entomopathogens in Aedes albopictus larvae

      P4.45 Gennaro Volpe (Naples)
      RNAi-mediated silencing of an immune gene in Spodoptera littoralis (Lepidoptera, Noctuidae) alters its embryonic development

      P4.46 Ehtisham Wahid (Bari)
      A Matlab-based algorithm for image quantification of yeast cell growth and survival on Agar plates

      P4.47 Monica Zoppè (Milan)
      Handling proteins. Tangible models in soft rubber allow composition of complex structures

      P4.48 Michela Zottini (Padua)
      Grafting as a new strategy for endophyte transferring in grapevine

      P4.49 Patrizia Contursi (Naples)
      Production of bioactive molecules from agri-food and lignocellulose biomasses using a novel strain of Weizmannia coagulans

    • P5 • Food and Nutrition

      P5.1 Cristina Angeloni (Ravenna)
      Anti-inflammatory and antioxidant activities of essential oil from Cannabis sativa in activated microglial cells

      P5.2 Attilio Anzano (Portici, NA)
      Metabolomic analysis and antimicrobial activity of Moringa oleifera seeds, leaves and oil

      P5.3 Benedetta Bottiglione (Bari)
      Red and blue light-emitting diode differently affect physiological parameters in lentil seedlings

      P5.4 Maria Cammareri (Portici, NA)
      Biotechnological approaches to increase triterpene production in sweet pepper

      P5.5 Benedetta Cerasuolo (Sesto Fiorentino)
      Dietary shift from traditional rural Tanzanian to globalized diet significantly affects the gut mycobiome

      P5.6 Sofia Chioccioli (Florence)
      Faecal microbiome as determinant of the effect of diet on colorectal-cancer risk:
      comparison of red meat based versus pesco-vegetarian diets in rodent models

      P5.7 Alessandra Cona (Rome)
      Plant-based biorepellents against large white butterfly caterpillars in Brassica oleracea

      P5.8 Patrizia D'Aquila (Rende, CS)
      Effects on bacterial growth and Quorum Sensing of Essential Oils from aromatic plants

      P5.9 Ida De Chiara (Caserta)
      In vitro evaluation of probiotic properties of newly LAB strains isolated from natural whey cultures

      P5.10 Marta Del Bianco (Rome)
      Microgreen production for space applications and earth benefit

      P5.11 Francesca Ferranti (Rome)
      The SOLE project: a plant greenhouse demonstrator for fresh food production in space

      P5.12 Venera Ferrito (Catania)
      A molecular strategy for species recognition: the Sparidae family as a case report

      P5.13 Silvana Hrelia (Rimini)
      The impact of Lactiplantibacillus Plantarum fermentation on the antioxidant and immunomodulatory properties of Vaccinium Floribundum berries

      P5.14 Veronica Panichi (Bologna)
      Oleuropein and hydroxytyrosol in cartilage protection: molecular mechanisms

      P5.15 Stefania Peddio (Monserrato)
      Protein alpha amylase inhibitors from Sardinian common beans cultivars: biological activity and phylogenetic analysis

      P5.16 Alessandro Vitale (Milan)
      Marked increase of globulin-1S in seeds of the italian purple maize (Zea mays) Moradyn variety

      P5.17 Pasquale Perrone (Naples)
      Olive oil phenols prevent mercury and calcium induced phosphatidylserine exposure and morphological changes in human erythrocytes

      P5.18 Valentina Ramundi (Rome)
      Wild edible plants chemical profile and their antimicrobial properties

      P5.19 Samuele Risoli (Pisa)
      Biocontrol of Fusarium Head Blight in wheat (Triticum spp.): A meta-analysis

      P5.20 Giuseppe Sabbioni (Ferrara)
      Properties of Arabidopsis thaliana P5C synthetase 1 enable stress-induced proline accumulation

      P5.21 Daniel Savatin (Viterbo)
      Re-Waste: a green, sustainable and circular strategy for crop resilience

      P5.22 Marta Toccaceli (Milan)
      Anti-inflammatory effect of upland potato varieties in THP-1 macrophages

      P5.23 Alessandra Villani (Bari)
      Changes in antioxidant metabolism and growth rate of wild rocket Diplotaxis tenuifolia (L.) DC as affected by different nutrient supply levels and growing systems

      P5.24 Nicola Landi (Caserta)
      Nutritional values and amino acid content of ‘Curniciello’ beans grown in ‘Piana di Monte Verna’ district, Italy

      P5.25 Giorgia Maria Varalda (Rome)
      Unexpected genotoxic activity of two non-volatile nitrosamines, N-nitroso-thiazolidine-4-carboxylic acid (NTCA) and N-nitroso-2-methyl-thiazolidine-4-carboxylic acid (NMTCA)

      P5.26 Cristina Nali (Pisa)
      Physiological changes induced by a pulse of ozone improve grapevine defence against Botrytis cinerea

    • P6 • Health and Disease

      P6.1 Saverio Alberti (Messina)
      Giant recursive cell membrane platforms drive calcium, phosphatidylinositol and kinase signaling

      P6.2 Mariaevelina Alfieri (Naples)
      Identification of uPAR variants acting as ceRNAs in leukaemia cells

      P6.3 Maria Laura Amenta (Naples)
      Functional analysis of acetylcholine signaling in Drosophila melanogaster immune response to bacterial pathogens

      P6.4 Francesca Ascenzi (Rome)
      Lung Adenocarcinoma cells cultured as 3D spheroids and enriched for Cancer Stem Cells undergo a phenotypic switch associated with resistance to ferroptotic cell death

      P6.5 Francesca Romana Auciello (Rome)
      Metabolism and tumour plasticity

      P6.6 Daniela Bellincampi (Rome)
      Olive mill waste water valorization: bioactive molecules-enriched fractions recovered by tangential-flow membrane filtration (TFMF) to elicit plant defence responses

      P6.7 Dina Bellizzi (Rende, CS)
      Blood circulating bacterial DNA in COVID-19 patients

      P6.8 Valentina Bigini (Viterbo)
      Increasing durum wheat resistance to Fusarium graminearum by using cell wall-derived oligogalacturonides

      P6.9 Chiara Brignola (Naples)
      MDM2/4 inhibitors as novel therapeutic strategy to enhance 5-FU induced nucleolar stress and apoptosis in colon cancer cells

      P6.10 Francesca Bruno (Catania)
      Human gene polymorphisms and the resistance to SARS-CoV-2 infection

      P6.11 Roberto Campagna (Ancona)
      Role of paraoxonase-2 in triple-negative breast cancer: effect of shRNA-mediated gene silencing on cell proliferation and chemosensitivity

      P6.12 Nicoletta Campolattano (Caserta)
      Characterization of the MSMEG-3762/63 efflux pump in Mycobacterium smegmatis

      P6.13 Barbara Carrese (Naples)
      Doxorubicin loaded albumin modified nanoparticles for targeted chemo-photothermal therapy in HS578T breast cancer cells

      P6.14 Francesca Carriero (Pavia)
      Photodynamic therapy using berberine photosensitizing to induce apoptosis in human astrocytoma established cells

      P6.15 Luca Cavinato (Rome)
      Trikafta therapy improves cystic fibrosis monocytes antimicrobial activity against Pseudomonas aeruginosa

      P6.16 Armando Cevenini (Naples)
      Compromission of endolysosomal functions in cellular models of methylmalonic acidemia

      P6.17 Roberta Chiavetta (Palermo)
      Applying RNA editing technology to correct the W1282X stop mutation in the CFTR mRNA in human bronchial cells

      P6.18 Ernesto Comite (Portici, NA)
      Application of microbial inoculants on food crops in Kenya and evaluation of rhizosphere microbiota

      P6.19 Federica Corrao (Palermo)
      LPS Responsive Beige-Like Anchor (LRBA) protein rescue by treatment with Translational Readthrough Inducing Drugs (TRIDs) in human fibroblasts harboring the c.5047 C>T (R1683*) nonsense mutation

      P6.20 Alessia Cuccurullo (Pontecagnano)
      Resistance against broomrapes (Orobanche and Phelipanche spp.) in tomato: phenotypic comparison of CRISPR/Cas9 tomato mutants targeting genes responsible for the biosynthesis of strigolactones

      P6.21 Antonino Cucinotta (Rome)
      Blocking the hedgehog-dependent tumor growth by a new selective endoplasmic reticulum aminopeptidase 1 inhibitor

      P6.22 Eleonora Da Pozzo (Pisa)
      Intermittent hypoxia promotes cellular priming and exaggerated inflammatory response of human microglia in vitro.

      P6.23 Marco Dainelli (Florence)
      Under fungal attack on a microplastic-contaminated soil: a case study on Arabidopsis thaliana

      P6.24 Valeria De Pasquale (Naples)
      Molecular mechanisms triggered by heparan sulfate proteoglycans in Mucopolysaccharidosis lysosomal diseases

      P6.25 Tonia De Simone (Verona)
      New miR-34a target genes identification by applying the CRISPR / Cas9 system for the generation of human miR-34a knock-out cell lines

      P6.26 Samuele Di Cristofano (Rome)
      CD38 restrains the activity of cGAMP released by multiple myeloma cells through enzymatic breakdown.

      P6.27 Francesca Di Modugno Damiani (Rome)
      Tumoral and stromal hMENA isoforms influence tertiary lymphoid structure localization and predict response to immunocheckpoint blockade in lung cancer patients

      P6.28 Matteo Digregorio (Pisa)
      Zebrafish knockout model to enlighten neurodevelopment defects and social impairments caused by setd5 loss of function

      P6.29 David Israel Escobar Marcillo (Rome)
      Obesity and genomic instability: a human longitudinal study after bariatric surgery

      P6.30 Giulia Fanelli (Rome)
      Role of MdtEF and AcrAB multidrug resistance efflux pumps in macrophage intracellular life of Adherent-Invasive Escherichia coli strain LF82

      P6.31 Maria Grazia Ferraro (Naples)
      Fighting triple negative breast cancer aggressive phenotype with novel Ru(III)-based nucleolipidic compounds

      P6.32 Giuseppe Forlani (Ferrara)
      Antiproliferative and phytotoxic effects of P5C reductase inhibitors do not rely upon proline starvation

      P6.33 Lorenzo Germelli (Pisa)
      Translocator Protein (TSPO, 18 kDa)-mediated neurosteroidogenesis regulates microglial functional phenotype

      P6.34 Luisa Gesualdi (Rome)
      Microgravity exposure induces antioxidant barrier deregulation and mitochondrial structure alterations in TCam-2 cells

      P6.35 Chiara Giacomelli (Pisa)
      COVID-19 and plasma level of the hypoxia inducible factor 1 subunit alpha (HIF1α): effect of ACE2 inhibition on bronchial and alveolar epithelial cells

      P6.36 Roberta Grillo (Naples)
      S-Adenosylmethionine inhibits colorectal cancer cell migration by upregulating the expression of miRNA-34/449 superfamily

      P6.37 Ciro Iaccarino (Sassari)
      LRRK2 and the exocyst complex: possible therapeutic option for Parkinson's disease?

      P6.38 Giuseppina Iacomino (Portici, NA)
      Biological effects of biochar-derived smoke-water on insects and plants

      P6.39 Matilda Iemmolo (Palermo)
      Alzheimer patients cerebrospinal fluid effects on neurons/astrocytes/microglia co-culture system

      P6.40 Angela Karimpour Ghahnavieh (Rome)
      GOLPH3 protein controls organ growth by interacting with TOR signaling proteins in Drosophila.

      P6.41 Rossella La Grotta (Rende, CS)
      Circulating miR-181a as a novel potential plasma biomarker for multimorbidity burden in the older population

      P6.42 Francesco Loreto (Florence)
      Proteome and volatilome profile changes induced in Phaseolus vulgaris by Colletotrichum lindemuthianum infection

      P6.43 Andrea Magrì (Catania)
      NHK1 peptide counteracts mitochondrial accumulation of SOD1 mutant 
      and improves the respiratory profile of a cellular ALS model

      P6.44 Claudia Martini (Pisa)
      The role of HIF-1α to predict cognitive disorders in OSAS patients: a pilot study

      P6.45 Stefania Martucciello (Fisciano,SA)
      Tbx1 interacts with Vegfr3 to regulate cardiac morphogenesis

      P6.46 Maria Benedetta Mattei (L'Aquila)
      Characterization of a novel member of the Arabidopsis berberine bridge enzyme-like protein family that specifically oxidizes cellulose oligomers and mixed-linked β-1➝3/ β-1➝4-glucans

      P6.47 Luigia Meo (Fisciano (SA))
      Characterization of a urokinase receptor variant

      P6.48 Paola Minghetti (Milan)
      Conditional marketing authorisation: a “lifeboat” for unmet medical needs 

      P6.49 Vittoria Monaco (Naples)
      Spike S1 domain interactome in non-pulmonary systems: possible novel roles beyond the receptor recognition

      P6.50 Shirin Navacci (Rome)
      The CRL3REN/KCTD11/SALL4/HDAC1 axis promotes Hedgehog-dependent medulloblastoma through GLI1 deacetylation

      P6.51 Valeria Nele (Naples)
      Self-Assembling Nanoparticles for RNA Delivery in the Treatment of Cancer

      P6.52 Giulia Oliveri (Alessandria)
      Alessandria biobank: origins, evolution and future scenarios

      P6.53 Simona Paladino (Naples)
      Endosomal trafficking and synaptojanin 1 (Synj1): a dangerous liaison

      P6.54 Gaetana Paolella (Fisciano,SA)
      Peculiar regulation of ER-stress and autophagy in cells from celiac patients

      P6.55 Marina Papaianni (Portici, NA)
      Biological properties of essential oils from Eucalyptus cinerea and Eucalyptus nicholii by-products

      P6.56 Carola Parolin (Bologna)
      Candida spp. biofilm formation is inhibited by vaginal Lactobacillus supernatants

      P6.57 Martina Pasqua (Rome)
      Investigating the relevance of the multidrug resistance efflux pump AcrAB-TolC during the invasive process of Shigella flexneri

      P6.58 Valentina Pastore (Rome)
      Inhibition of colistin resistance in Pseudomonas aeruginosa strains

      P6.59 Annalisa Pecoraro (Naples)
      Novel therapeutic strategy combining β-carotene with 5-FU to overcome uL3-mediated chemoresistance in colorectal cancer cells

      P6.60 Maria Pelullo (Rome)
      The activation of Jagged1 signaling by chemotherapeutic agents counteracts the Oxaliplatin/5FU-induced anti-cancer effects: a novel mechanism of drug resistance in CRC

      P6.61 Riccardo Perriera (Palermo)
      Nonsense suppression in human cystic fibrosis organoids (CFTRW1282X/dele2,3) by a new translational readthrough inducing drug (NV848) combined to CFTR modulators.

      P6.62 Marialuisa Piccolo (Naples)
      Ruthenium(III) complex chemotherapy efficacy boosting by interfering with cellular iron metabolism

      P6.63 Angela Pironti (Portici, NA)
      Treatments of Trichoderma harzianum strain M10 and benzothiazole derivatives on tomato plants (Solanum Lycopersicum) as biostimulant and plant protection products.

      P6.64 Daniela Pontiggia (Rome)
      Oligogalacturonide Oxidases (OGOXs) play a role in plant immunity and development

      P6.65 Giuseppe Quaratiello (Pisa)
      Hyperspectral detection of temporal and spatial development of wheat blast disease

      P6.66 Marta Ranesi (Portici, NA)
      Beauveria bassiana biocontrol of fungal diseases is independent of rhizosphere acidification

      P6.67 Stefano Ricagno (Milan)
      Ex-vivo structural biology: new insights on systemic amyloidosis

      P6.68 Anastasia Ricci (Urbino)
      New human ATM variants are able to regain ATM functions in ataxia telangiectasia disease

      P6.69 Alessandra Sacchi (Rome)
      Myeloid-derived suppressor cells from SARS-CoV-2 infected patients contribute to platelets activation and extracellular traps release

      P6.70 Bernardina Scafuri (Fisciano)
      Computational strategy to find pharmacochaperones for GALT enzyme

      P6.71 Rosario Luigi Sessa (Rome)
      Role of autophagy in Fibrodysplasia Ossificans Progressiva (FOP) disease

      P6.72 Chiara Stefani (Verona)
      Increased prevalence of HLA-C unstable variants in HIV-1 rapid progressor patients

      P6.73 Simona Titoli (Palermo)
      Exploring specific antisense oligonucleotides (ASOs) fused to ADARs recruiting domain to restore CFTR nonsense mutation

      P6.74 Paola Trono (Monterotondo, RM)
      hMENA isoforms regulate cancer specific Type I IFN signaling and extrinsic mechanisms of resistance to immune checkpoint blockade

      P6.75 Romualdo Varricchio (Rome)
      Human serum albumin protective role in SARS-CoV-2 infections

      P6.76 Daniele Viavattene (Turin)
      STAT3-mediated regulation of ER calcium release and apoptosis in triple negative breast cancer cells, downstream of mTOR and upstream of IP3R3

      P6.77 Francesco Vieceli Dalla Sega (Lugo, RA)
      Clonal hematopoiesis of indeterminate potential is associated with increased immune infiltration in the calcified aortic valve

      P6.78 Stefania Vitale (Portici, NA)
      Carbon and nitrogen sources regulate extracellular pH modulation and biocontrol activity in Trichoderma

      P6.79 Tiziana Zotti (Benevento)
      Peptides to discriminate individual antibody response: lessons from COVID-19 pandemic

      P6.80 Luisa Guttieri (Rome)
      Role of FGFR2c/PKCε signaling in the control of MCL-1-mediated cell survival and invasion in pancreatic ductal adenocarcinoma cells

      P6.81 Maria Franza (Rome)
      The CHK1 kinase inhibitor, MK-8776, induces the degradation of the oncogenic protein PML-RARα in retinoic acid-resistant acute promyelocytic leukemia cells

      P6.82 Ylenia Cerrato (Rome)
      Cytochrome c as a marker of oxidative stress in follicular thyroid cancer

      P6.84 Mauro Magnani (Urbino)
      Superparamagnetic nanoparticles encapsulated in red blood cells as novel contrast agents for diagnostic techniques in the biomedical field